Genomic analysis of the specimens revealed anti-cancer activity through the downregulation of specific genes that can promote tumor activity. Then, when tested on glioblastoma brain cancer cells, it was discovered that exposure inhibited several tumor proliferation processes, suggesting that someday antler velvet extract may play a role in treating this deadly cancer. The Tang studies and are the only published studies regarding PCa.
Neither involved human trials, nor have there been any published papers on antler extract in humans. Also, there is no published evidence that deer antler velvet extract can prevent cancer. The idea that it can prevent or cure PCa is speculative. Do not use yourself as test subject! Please re-read the blog below for more information. Take antlers on deer. In all deer species, the stags grow antlers female caribou or reindeer also produce antlers.
Around 6 months of age, a buck fawn will develop a pair of bumps called pedicles , the base from which antlers will grow. The growth cycle typically starts around April when the days are lengthening.
As the antlers begin the early surge in the summer months, they are not yet hard bone but instead feel spongy to the touch. While they are dynamically forming, they are rich in blood vessels and nerves. These are especially dense in the outer covering, a hairy skin called velvet. The stag needs velvet for antler formation because its blood vessels and nerves deliver growth factors and hormonal biochemicals. If the velvet is cut or removed during this time, it bleeds profusely and is very painful for the deer.
Meanwhile, mineral deposits such as calcium and phosphorus gradually fill in and replace the spongy tissue, turning the antlers into true bone.
As summer turns to fall, the increasing bone deposition starts to cut off the blood supply to the velvet. When this is complete, the velvet dries up and sheds from the antlers. The stag may rub its antlers against trees to facilitate the shedding, and deer have been observed eating their shed velvet. In traditional Chinese medicine, antler velvet has been used medicinally for thousands of years. In short, science supports theoretical health benefits.
In particular, velvet is rich in insulin-like growth factor 1 IGF-1 , a hormone that potentially offers anti-aging and performance-enhancing effects, but which may promote cancer development. Neither group differed significantly with respect to disease activity, pain experience and overall health status after six months of treatment. Results of this trial were given a lower weighting when we came to our conclusion about the compo. It causes joint pain and inflammation.
Learn about the symptoms, causes and treatment. Versus Arthritis About arthritis Complementary and alternative treatments Types of complementary treatments Antler velvet. Antler velvet. Download complementary and alternative medicines report. Print this page. What is antler velvet?
Family: Nutritional supplement of the Cervidae family Scientific name: Elk velvet antler Other names: Cervus elaphus, deer velvet, velvet deer antler Antler velvet is made from deer or elk antlers in early stages of their growth during the velvet stage. Researchers believe that the imbalance between cartilage erosion and regeneration in osteoarthritis suffers is caused by a lack of glycosaminoglycans.
Glycosaminoglycans play a vital role in the structural integrity of cartilage. The compound appears to inhibit enzymes that deplete cartilage nutrition.
Chondroitin sulfate molecules are long chains of sugars and sulfur that create tiny spaces filled with fluid. These spaces protect and cushion joints.
New Zealand research reports that although the mechanism is unknown, deer antler velvet shows strong anti-inflammatory effects. Recent clinical tests suggest oral ingestion of glycosaminoglycan-peptide complex, or components such as chondroitin sulfate and glucosamine sulfate — both found in deer antler velvet — may help stimulate cartilage repair.
In a double blind study Edelman, , 54 patients with arthritis in the knee were given deer antler velvet or a placebo and assessed at 1, 3 and 6 months. Patients treated with deer antler velvet showed improvement in pain and physical global assessment at 3 and 6 months. No significant improvement was observed for the placebo group for any of the parameters examined. According to modern research, deer antler velvet has shown gonadotropic activity.
Studies by both Fisher and Wang indicate that deer antler velvet may increase testosterone levels in men and can help prevent some conditions associated with aging.
The estrogen hormone most affected by deer antler velvet is estradiol. Estradiol is a precursor to testosterone. WebMD notes that deer antler velvet is used to increase libido, treat male erectile dysfunction, and improve fertility. Traditionally, deer antler velvet was used to remedy sexual disorders in men such as premature ejaculation, watery semen and impotence. For women, deer antler velvet can help ease the symptoms associated with pre-menstruation by relieving cramps, suppressing mood swings, and raising energy levels.
It is also used to treat vaginal discharges, uterine bleeding, menstrual disorders, infertility, and menopause. Russian researchers claim that compounds found in deer antler velvet can ease the effects of menopause in women. Also, it increases the synthesis of liver and kidney protein by promoting activity of other specific enzymes.
Reviews report that this research is strong evidence of the anti-aging influence of deer antler velvet. Recent studies in Japan show that deer antler velvet reduced signs normally associated with senility. This is probably due to its hormonal effects. Deer antler velvet has shown marked effects on biochemical parameters related to aging in mice, a model for senility. Wang Ben-Ziang found that deer antler velvet decreased activity of enzymes associated with aging process, increased levels of liver superoxide dismutase, a free radical scavenging enzyme, and increased liver and kidney protein synthesis by enhancing enzyme activity.
These effects are general evidence of anti aging. Research has shown that deer velvet supports the oxygen carrying capacity of blood, facilitating healthy blood pressure and circulation.
Blood pressure reduction is due to velvet antler's ability to increase dilation of the peripheral blood vessels. Russian and Japanese researchers have conducted experiments using deer antler extract and found that it appears to lower blood pressure in both human subjects and laboratory animals.
A series of clinical case studies Albov, were conducted in which the effects of Pantocrin on cardiac patients were assessed. Deer antler velvet has been shown to stimulate red blood cell synthesis in induced anemia in laboratory animals.
The polysaccharides in deer antler velvet have been linked to biological activities, such as improving circulation, reducing the blood's tendency to clot, decreasing risk of stroke, and improving general cardiovascular health. The effect of Pantocrin, a deer velvet extract, on mental performance was tested Taneyeva, undated on men aged years old. The subjects were asked to make corrections to text by substituting letters.
The subjects who used pantocrin scored higher than the control group. A study by Chen found that deer antler velvet inhibits monoamine oxidase activity in the liver and brain tissues of aged mice. Monoamine-oxidase inhibitors prevent breakdown of monoamine neurotransmitters such as norepinephrine and serotonin. Antler apparently allows these vital neurotransmitters to be available longer to the brain structure, enhancing mood.
Research in Korea, New Zealand and China has shown that deer antler velvet can stimulate the immune system. Extracts of deer antler velvet were variously shown to increase macrophage activity, stimulate the production of lymphocytes and increase the number of red and white blood cells.
A Russian study indicated that the amino acids, polypeptides and other compounds found in antler increased the survival rate of mice with cancerous tumors as much as 40 percent. The mice with tumors lost less weight and suffered lower levels of kidney damage than those treated with drugs. Tests with preparations of deer antler velvet have shown it to increase production of both red blood cells and white blood cells. A New Zealand study Suttie, found compelling evidence that extracts of deer antler velvet stimulated the human immune system, as measured by increased white blood cell production.
Deer antler velvet can be used for a variety of reasons:. Deer antler velvet is a natural, well tolerated, non-toxic dietary supplement.
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